DKCandBP / Laboratory of Kinetic Modeling

Scientific direction:

Development and application of kinetic methods for studying complex processes in chemical and biological systems.

Main tasks:

• Study of kinetic regularities and biochemical mechanisms of oxidative processes in erythrocytes under the action of nitric oxide and peroxidation initiators. Erythrocyte as a model of cytotoxicity of endogenous metabolites and xenobiotics. Study of the antioxidant action of inhibitors of various nature.
• Investigation of the influence of nitrosyl complexes of iron - donors of nitrogen monoxide on the energy metabolism of the cell, the study of the biological activity of nitrosyl complexes in relation to glycolysis products and glycolytic enzymes.
• Investigation of the reactions of homolytic and heterolytic routes of spending of aromatic and aliphatic oxiranes in polycomponent systems "epoxide - catalyst (acid, transition metal salt)" in the medium of aliphatic alcohols of different structure.
• Study of kinetic regularities and mechanism of liquid-phase oxidation of hydrocarbon compounds with tense structure.